Early-Stage Kidney Cancer: Diagnosis & Treatment

Introduction

Ovarian cancer develops in the ovaries, which are part of the female reproductive system. It is one of the most treatable cancers when detected early (Stage 1 & 2), with survival rates exceeding 90% when properly treated. However, due to vague symptoms, early detection remains a challenge.

Germany is a leading destination for ovarian cancer treatment, offering:

  • Advanced diagnostics (transvaginal ultrasound, CA-125 blood tests, genetic testing)
  • Minimally invasive & fertility-preserving surgeries
  • HIPEC (Hyperthermic Intraperitoneal Chemotherapy) for localized treatment
  • Proton therapy & targeted therapy for precision treatment

    • International patients benefit from Germany’s top gynecologic oncology specialists, cutting-edge hospitals, and innovative ovarian cancer treatment approaches.

    Understanding Early-Stage Ovarian Cancer

    - Stage 1 Ovarian Cancer

    Cancer is confined to one or both ovaries.

    No spread to lymph nodes, abdominal tissues, or distant organs.

  • Subcategories:

    • • Stage 1A: Tumor is in one ovary only, without rupture.
    • • Stage 1B: Tumor is in both ovaries, but still confined.
    • • Stage 1C: Tumor has ruptured or cancer cells are found in abdominal fluid.

    - Stage 2 Ovarian Cancer

    Cancer has spread beyond the ovaries to nearby pelvic organs (uterus, fallopian tubes, bladder, rectum, or peritoneum).

    No distant metastases.

  • Subcategories:

    • • Stage 2A: Cancer has spread to the fallopian tubes or uterus.
    • • Stage 2B: Cancer has spread to nearby pelvic organs (bladder, rectum, or sigmoid colon).

    Why Early Detection Matters

    • Transvaginal ultrasound & CA-125 blood tests help detect ovarian cancer before it spreads.

    • Genetic testing (BRCA1/BRCA2, MSI, TP53) guides personalized therapy selection.

    Treatment Options for Stage 1 & 2 Ovarian Cancer

    1️⃣ Fertility-Preserving Surgery (For Young Patients with Early-Stage Cancer)

  • Definition: A surgical procedure that removes the cancerous ovary while preserving the uterus and the unaffected ovary to allow future pregnancy.

    • • Procedure: Unilateral salpingo-oophorectomy (removal of one ovary & fallopian tube).

    • Ideal for: Stage 1A or 1B patients who wish to have children.

    • Cost: €15,000 – €35,000

    • Prognosis: 95%+ survival rate when combined with careful monitoring.

    2️⃣ Total Hysterectomy & Bilateral Salpingo-Oophorectomy (Standard Surgery for Stage 1 & 2)

  • Definition: A surgical procedure to remove the uterus, both ovaries, and fallopian tubes, reducing recurrence risks.

    • • Procedure Performed laparoscopically, robotically, or via open surgery.

    • Ideal for: Stage 1C & Stage 2 patients or those with genetic mutations (BRCA, TP53).

    • Cost: €25,000 – €55,000

    • Prognosis: 90%+ survival rate for early-stage disease.

    3️⃣ Lymphadenectomy (Lymph Node Removal for Staging & Prevention)

  • Definition: A procedure to remove pelvic & para-aortic lymph nodes to check for microscopic cancer spread.

    • • Procedure: Can be performed during primary surgery (hysterectomy).

    • Ideal for: All early-stage ovarian cancer patients to ensure complete staging.

    • Cost: €5,000 – €12,000

    • Prognosis: Helps determine need for additional therapy.

    4️⃣HIPEC (Hyperthermic Intraperitoneal Chemotherapy) – Heated Chemotherapy During Surgery

  • Definition: A heated chemotherapy treatment applied directly into the abdomen during surgery, killing microscopic cancer cells.

    • • Procedure: Performed immediately after tumor removal.

    • Ideal for: Stage 2 ovarian cancer with peritoneal involvement.

    • Cost: €30,000 – €60,000

    • Prognosis: Reduces recurrence risks by 30-50%.

    5️⃣Chemotherapy (For Stage 1C & Stage 2 Patients)

  • Definition:The use of anti-cancer drugs to destroy remaining tumor cells after surgery.

    • • Common drugs: Carboplatin + Paclitaxel (standard regimen).

    • Ideal for: High-risk Stage 1C & all Stage 2 cases.

    • Cost: €10,000 – €30,000 per cycle

    • Prognosis: Enhances survival & prevents recurrence.

    6️⃣Proton Therapy (For Precision Radiation & Organ Preservation)

  • Definition: A highly advanced radiation therapy that delivers proton beams directly to the tumor, minimizing damage to healthy tissue.

    • • Ideal for : Patients with residual disease after surgery.

    • Cost: €50,000 – €100,000 per treatment plan

    • Prognosis: Improves local control while reducing side effects.

    7️⃣Targeted Therapy & Immunotherapy (For Specific Cases)

  • Definition: Precision medicine that blocks cancer growth signals (targeted therapy) or boosts the immune system (immunotherapy).

    • • Types:

    PARP inhibitors (Olaparib, Niraparib): For BRCA-mutated ovarian cancer.

    Anti-VEGF Therapy (Bevacizumab): Prevents blood vessel growth in tumors.

    Checkpoint Inhibitors (Pembrolizumab): For MSI-high or PD-L1-positive tumors.

    • Cost: €40,000 – €90,000 per treatment plan

    • Prognosis: Extends survival & prevents recurrence.

    •Dendritic Cell Therapy for Ovarian Cancer

    Definition: Dendritic cells (DCs) are modified to recognize and destroy ovarian cancer cells, strengthening the immune system.

    • Best for:

  • Women with BRCA-mutated or recurrent ovarian cancer.
  • Patients seeking personalized immune-based therapy.

    • • Cost: €30,000 – €60,000 per treatment plan plan

    • Prognosis: Boosts immune response & reduces recurrence risk.

    • Leading Dendritic Cell Therapy Centers in Germany

    • 🏥 University Hospital Heidelberg (NCT)
    • 🏥 Charité – Universitätsmedizin Berlin
    • 🏥 IOZK Cologne

    • Why Germany is the Best Destination for Ovarian Cancer Treatment

  • Top gynecologic oncology centers
  • Minimally invasive surgery for fertility preservation
  • Proton therapy for precise radiation treatment
  • Dendritic cell therapy & cutting-edge immunotherapy

    • Top Pancreatic Cancer Specialists in Germany

    • 1. Prof. Dr. Jalid Sehouli – Charité Berlin (Gynecologic Oncology Expert).
    • 2. Prof. Dr. Sven Mahner – LMU Klinikum Munich (Advanced Cervical Cancer Treatment).
    • 3. Prof. Dr. Andreas du Bois – Essen University Hospital (Ovarian Cancer Research & Treatment).

    Conlusion

    Germany is a global leader in ovarian cancer treatment, offering fertility-preserving surgery, HIPEC, proton therapy, and dendritic cell immunotherapy.

    Start Your Journey with WEGOVITA

    Submit your request now! You will receive an individual evaluation of your case within 48 hours and get a scheduled appointment within 3 weeks to start your recovery journey with WEGOVITA.

    📌 Sources for Ovarian Cancer Treatment