Adrenal Cancer

Adrenal Cancer: Advanced Diagnosis & Treatment in Germany

Expert endocrine oncology with surgical precision and integrative care

 What Is Adrenal Cancer?

Adrenal cancer, or adrenocortical carcinoma (ACC), is a rare and aggressive cancer of the adrenal cortex — the hormone-producing outer layer of the adrenal glands located atop each kidney.

This malignancy can disrupt hormone levels (e.g., cortisol, androgens, aldosterone), affecting metabolism, reproduction, blood pressure, and immune function. Though rare, adrenal cancer demands early, expert intervention due to its fast-growing nature and potential to spread.

Key Facts & Global Statistics

The key to better outcomes lies in early detection, complete surgical resection, and access to expert care.

Symptoms of Adrenal Cancer

Functional (Hormone-Producing) Tumors:

• Rapid weight gain or muscle weakness (Cushing’s syndrome)

• High blood pressure, high blood sugar

• Virilization (excess facial/body hair in women)

• Feminization (breast development in men)

• Irregular menstrual cycles or infertility

Non-Functional Tumors:

• Abdominal or back pain

• Fullness or palpable mass

• Unexplained fatigue or weight loss

Diagnosis: Precision Imaging and Hormone Profiling in Germany

Germany offers one of the most comprehensive diagnostic protocols for adrenal cancer, including:

In Germany, the use of radioactive tracers helps detect even microscopic residual cancer cells post-surgery — increasing treatment accuracy and long-term outcomes.

Treatment: Advanced, Minimally Invasive, and Multidisciplinary

1. Minimally Invasive Adrenal Surgery

Germany prioritizes laparoscopic and robot-assisted adrenalectomies for smaller, localized tumors — offering faster recovery and fewer complications.

German endocrine surgeons are among the most experienced in complete (R0) resection — a crucial factor for long-term survival.

2. Medical Therapy

3. Radiotherapy

• Stereotactic Body Radiotherapy (SBRT) for local control and metastases

• Adjunctive use after incomplete resection or high-risk tumors

4. Biological & Immune-Supportive Therapy (Germany’s Holistic Advantage)

Germany integrates biological immunotherapy and body-strengthening protocols to support recovery, immune function, and hormonal balance:

 “My body felt stronger after each step.Many thanks to Yasmine my medical coordinator in WEGOVITA and Lisa who was my interpreter…very great team”
— Anna D., 42,Romania,treated in Frankfurt am Main

5. Dendritic Cell Therapy?

Dendritic cells are key players in the immune system. They act as “messengers” that present antigens (like cancer cells) to T-cells, which then attack the tumor.
In dendritic cell therapy, a patient’s own immune cells are collected, programmed in a lab to recognize tumor-specific markers, and then reinfused into the body to stimulate a targeted immune response.

Can It Help in Adrenal Cancer?

While adrenal cancer is rare and not yet widely studied in the context of dendritic cell therapy, emerging research and compassionate use cases in Germany suggest:

•  Potential benefits in hormone-producing, treatment-resistant tumors

•  Can be combined with mitotane or checkpoint inhibitors to improve immune sensitivity

•  Minimally toxic, personalized, and immune-strengthening

•  Promotes immune surveillance to prevent recurrence

 In Germany, dendritic cell vaccines are used in highly specialized cancer immunotherapy centers, especially for patients with:

• Recurrent or inoperable adrenal tumors

• Metastases after standard treatments

• Good general health but limited systemic options

Germany’s Advantage

Germany is a pioneer in dendritic cell research and application, offering:

• GMP-certified cell labs (e.g., in Cologne, Munich, Berlin)

• Personalized tumor antigen profiling

• Combination with biological immunotherapy and vitamin-based support

• Access through individual therapy plans and experimental protocols

 When Is It Considered?

Dendritic cell therapy is not yet a first-line standard treatment for adrenal cancer. It is considered an individualized or compassionate-use therapy, often part of integrative cancer protocols in Germany.

Why Germany? Expertise You Can Trust

Germany is a global center of excellence in endocrine oncology, offering:

 Dedicated adrenal tumor units with top-tier surgeons
 Use of radio-guided surgery and robot-assisted techniques
 Access to molecular diagnostics & clinical trials
 Integration of conventional & complementary therapies
 Focus on preserving hormone balance and patient quality of life

 German centers report >90% complete resection success in localized cases, with significantly lower recurrence rates than global averages.

WEGOVITA: Your Pathway to Top Adrenal Cancer Care in Germany

WEGOVITA helps international patients access Germany’s best care with confidence and personalized support:

Selection of certified adrenal surgery centers

 Coordination of diagnosis, surgery, and therapy
 Medical record translation & second opinions
 Visa support, accommodation, and interpreters
  Post-treatment follow-up, rehab, and nutrition

 German Clinical Outcomes at a Glance

Summary

Adrenal cancer is rare — but demands rare expertise.
Germany offers world-leading care that blends high-precision surgery, molecular imaging, and whole-body support to achieve better survival and long-term wellbeing.

With WEGOVITA, you gain not just access to care — but a dedicated partner by your side at every step.